Fig. 4

A female patient aged 27 years old, known to have RRMS with EDSS score of 6. I. Cortex segmentation: raw T1WI axial plane (A), T1W image after brain extraction (B), gray and white matter segmentation (C) and cortex segmentation (D). II. Surface reconstruction: T1W image with pial surface (red line) and white matter surface (yellow line) (E) and surface reconstruction (F). III. Cortical thickness results in mm: The patient had significant decrease in the mean cortical thickness (1.848 mm, 1.984 mm), and the precentral (1.4775 mm, 1.4551 mm), postcentral (1.2831 mm, 1.3847 mm), paracentral (1.5146 mm, 1.6518 mm) and posterior cingulate cortices (1.7551 mm, 1.8517 mm) in left and right side, respectively, and left Inferior Temporal (1.7343 mm) and left Lateral Occipital (1.6943 mm) cortices