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Table 3 Correlation between duration of disease, EDSS and the number of attacks per year and the number of MS plaques in different anatomical regions

From: Diagnostic utility of 3D DIR MRI in the estimation of MS lesions overall load with special emphasis on cortical subtypes

MS plaque location

Duration

EDSS

Attacks per year

ρ+

p value

ρ+

p value

ρ+

p value

Cortical type I

0.260

0.018*

0.356

0.001*

0.154

0.167

Cortical type II

0.244

0.027*

0.197

0.076

0.291

0.008*

Cortical type III

0.354

0.001*

0.260

0.018*

0.269

0.014*

Cortical type IV

− 0.007

0.952

0.016

0.889

− 0.033

0.769

Overall cortical types

0.342

0.002*

0.368

0.001*

0.296

0.007*

Juxtacortical

0.258

0.019*

0.134

0.229

0.280

0.011*

Juxtacortical expanded

0.379

< 0.001*

0.343

0.002*

0.348

0.001*

Deep gray matter

− 0.022

0.841

− 0.114

0.308

− 0.047

0.675

Subcortical WM

0.240

0.030*

0.088

0.430

0.307

0.005*

Deep WM

0.594

< 0.001*

0.183

0.099

0.478

< 0.001*

Periventricular WM

0.366

0.001*

0.281

0.010*

0.252

0.022*

Infratentorial

0.123

0.272

0.083

0.46

0.061

0.585

Overall MS burden

0.640

< 0.001*

0.359

0.001*

0.525

< 0.001*

  1. +Spearman correlation
  2. *Significant