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Table 3 Correlation between duration of disease, EDSS and the number of attacks per year and the number of MS plaques in different anatomical regions

From: Diagnostic utility of 3D DIR MRI in the estimation of MS lesions overall load with special emphasis on cortical subtypes

MS plaque location Duration EDSS Attacks per year
ρ+ p value ρ+ p value ρ+ p value
Cortical type I 0.260 0.018* 0.356 0.001* 0.154 0.167
Cortical type II 0.244 0.027* 0.197 0.076 0.291 0.008*
Cortical type III 0.354 0.001* 0.260 0.018* 0.269 0.014*
Cortical type IV − 0.007 0.952 0.016 0.889 − 0.033 0.769
Overall cortical types 0.342 0.002* 0.368 0.001* 0.296 0.007*
Juxtacortical 0.258 0.019* 0.134 0.229 0.280 0.011*
Juxtacortical expanded 0.379 < 0.001* 0.343 0.002* 0.348 0.001*
Deep gray matter − 0.022 0.841 − 0.114 0.308 − 0.047 0.675
Subcortical WM 0.240 0.030* 0.088 0.430 0.307 0.005*
Deep WM 0.594 < 0.001* 0.183 0.099 0.478 < 0.001*
Periventricular WM 0.366 0.001* 0.281 0.010* 0.252 0.022*
Infratentorial 0.123 0.272 0.083 0.46 0.061 0.585
Overall MS burden 0.640 < 0.001* 0.359 0.001* 0.525 < 0.001*
  1. +Spearman correlation
  2. *Significant