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Table 2 Results of MRI parameters in relation to pathologic response (n = 25)

From: Predicting pathological response of locally advanced breast cancer to neoadjuvant chemotherapy: comparing the performance of whole body 18F-FDG PETCT versus DCE-MRI of the breast

 

pCR (n = 8)

Non-pCR (n = 17)

p value

Median

(Range)

Median

(Range)

MRI baseline

     

Max. diameter (cm)

3.8

(1.6–5.6)

5.5

(2.5–15.0)

0.027

ADC value

0.5

(0.3–0.9)

0.4

(0.3–0.8)

0.711

Max. enhancement %

123.5

(66.0–185.0)

72.0

(8.0–102.0)

0.001

MRI interim

     

Max. diameter (cm)

2.8

(1.9–5.0)

3.5

(1.3–12.0)

0.576

ADC value

0.8

(0.4–1.2)

0.5

(0.3–3.0)

0.711

Max. enhancement %

52.5

(25.0–117.0)

40.0

(8.5–90.0)

0288

MRI (baseline vs interim)

     

Max. diameter (cm) regression %

30.5

(8.0–100.0)

35.0

(4.0–64.0)

0.016

ADC % change

37.5

(25.0–79.0)

16.7

(0.0–84.0)

0.932

Max. enhancement regression %

56.0

(12.0–79.0)

21.0

(0.0–84.0)

0.049

  1. Bold means the parameter was significant p-value < 0.05