| |
pCR (n = 8)
|
Non-pCR (n = 17)
|
p value
|
|---|
|
Median
|
(Range)
|
Median
|
(Range)
|
|---|
|
MRI baseline
| | | | | |
|
Max. diameter (cm)
|
3.8
|
(1.6–5.6)
|
5.5
|
(2.5–15.0)
|
0.027
|
|
ADC value
|
0.5
|
(0.3–0.9)
|
0.4
|
(0.3–0.8)
|
0.711
|
|
Max. enhancement %
|
123.5
|
(66.0–185.0)
|
72.0
|
(8.0–102.0)
|
0.001
|
|
MRI interim
| | | | | |
|
Max. diameter (cm)
|
2.8
|
(1.9–5.0)
|
3.5
|
(1.3–12.0)
|
0.576
|
|
ADC value
|
0.8
|
(0.4–1.2)
|
0.5
|
(0.3–3.0)
|
0.711
|
|
Max. enhancement %
|
52.5
|
(25.0–117.0)
|
40.0
|
(8.5–90.0)
|
0288
|
|
MRI (baseline vs interim)
| | | | | |
|
Max. diameter (cm) regression %
|
30.5
|
(8.0–100.0)
|
35.0
|
(4.0–64.0)
|
0.016
|
|
ADC % change
|
37.5
|
(25.0–79.0)
|
16.7
|
(0.0–84.0)
|
0.932
|
|
Max. enhancement regression %
|
56.0
|
(12.0–79.0)
|
21.0
|
(0.0–84.0)
|
0.049
|
- Bold means the parameter was significant p-value < 0.05
