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Table 2 Results of MRI parameters in relation to pathologic response (n = 25)

From: Predicting pathological response of locally advanced breast cancer to neoadjuvant chemotherapy: comparing the performance of whole body 18F-FDG PETCT versus DCE-MRI of the breast

  pCR (n = 8) Non-pCR (n = 17) p value
Median (Range) Median (Range)
MRI baseline      
Max. diameter (cm) 3.8 (1.6–5.6) 5.5 (2.5–15.0) 0.027
ADC value 0.5 (0.3–0.9) 0.4 (0.3–0.8) 0.711
Max. enhancement % 123.5 (66.0–185.0) 72.0 (8.0–102.0) 0.001
MRI interim      
Max. diameter (cm) 2.8 (1.9–5.0) 3.5 (1.3–12.0) 0.576
ADC value 0.8 (0.4–1.2) 0.5 (0.3–3.0) 0.711
Max. enhancement % 52.5 (25.0–117.0) 40.0 (8.5–90.0) 0288
MRI (baseline vs interim)      
Max. diameter (cm) regression % 30.5 (8.0–100.0) 35.0 (4.0–64.0) 0.016
ADC % change 37.5 (25.0–79.0) 16.7 (0.0–84.0) 0.932
Max. enhancement regression % 56.0 (12.0–79.0) 21.0 (0.0–84.0) 0.049
  1. Bold means the parameter was significant p-value < 0.05