Fig. 1

A 56-year-old female patient complaining of continuous bloody nipple discharge from the left breast. Mammography MLO (a, b) and CC views (c, d) showed extremely dense breast parenchyma (ACR D). An ultrasound (e, f) was performed and dilated ducts with non-vascular echogenic contents were identified. Cytology was performed and revealed atypical epithelial cells, suspicious but inconclusive for malignancy. CESM in MLO (g, h) and CC views (i, j) showed intense, heterogeneous, regional, non-mass enhancement and was categorized as BI-RADS 4. Pathology revealed DCIS. MLO, mediolateral oblique; CC, craniocaudal, CESM, contrast-enhanced spectral mammography; DCIS, ductal carcinoma in situ