Author | Year | IVIM mean (× 10−3 mm2/s) or % change | Tumor size | P value | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre-NAC | Post-NAC | Before NAC (cm) | After NAC (cm) | %Change | |||||||||||||
Response or Baseline | Nonresponse | Response | Nonresponse | ||||||||||||||
D | D* | F | D | D* | F | D | D* | F | D | D* | f | ||||||
Suo et al. [35] | 2021 | 1.00 ± 0.83 | 15.62 ± 4.18 | 9.27 ± 3.66 | 0.98 ± 0.80 | 15.44 ± 3.70 | 9.27 ± 2.98 | 0.78 ± 0.68 |  − 3.06 ± 6.36 | 1.78 ± 4.33 | 0.25 ± 0.35 |  − 1.97 ± 6.35 | 0.82 ± 3.86 | 39.8 ± 21.2 | NA |  − 34.0 ± 18.9 | 0.009 |
Kim et al. [36] | 2018 | 1.22 | 5.87 | 45.17 | 1.10 | 7.33 | 43.33 | 1.37↑ | 6.04↑ | 49.56↑ | 1.15↑ | 6.58↓ | 45.23↑ | 4.15 (2.2–9.3) | 3.05 (1.1–7.8) |  − 20.22 (− 54.9–4.4) | 0.023 |
Cho et al. [37] | 2017 | 1.02 | 25.05 | 8.8 | NA | NA | NA | 0.99↓ | 25.54↑ | 8.7↓ | 1.05↑ | 17.16↓ | 11.7↑ | 13.84 (3.43, 44.45) | 13.80 (3.43, 37.00) |  − 40.2% | 0.452 |
Che et al. [38] | 2016 | 0.92 | 10.10 | 32.40 | 0.83 | 9.40 | 24.40 | 1.36 ± 0.30↑ | 8.98↓ | 14.51 ± 7.25↓ | 0.98 ± 0.23↑ | 20.00↑ | 20.69 ± 5.10↓ | 4.89–1.52 | 2.57 (2.03, 4.16) |  − 39.2% |  < 0.001 |
Bedair et al. [39] | 2017 | 0.85 ± 0.05 | NA | 12.10 ± 2.02 | 1.02 ± 0.05 | NA | 10.32 ± 1.15 | 1.30 ± 0.14 (↑36%) | NA | 8.48 ± 1.54 (↓29%) | 1.28 ± 0.15 (↑23%) | NA | 10.53 ± 2.51 (↑5%) | 1.2–12 | 4.1 ± 0.4 | 1.5 ± 0.2 | 0.14 |