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Table 4 Quantitative ROC curve analysis cutoff values for tibial nerve CSA and stiffness between patients with DPN and control/DM groups to detect diabetic peripheral neuropathy

From: Diagnostic value of shear wave ultrasound elastography of tibial nerve in patients with diabetic peripheral neuropathy

Variable Mean Stiffness value (at cutoff = 86.5 kPa) CSA by US (at cutoff = 14.5 mm2)
Control/DM group (n = 200 TN) 56.16 ± 21.39 10.71 ± 2.04
DPN group (n = 100 TN) 97.94 ± 19.55 16.72 ± 1.89
P value < 0.001 0.074
Sensitivity (%) 94.6 71
Specificity (%) 93.8 69
AUC (area under curve) 0.975 0.671
NPV (%) 95 64.5
PPV (%) 93 67.8
  1. CSA cross−sectional area, DM Diabetes mellitus, DPN Diabetic peripheral neuropathy, kPa kilopascals, NPV Negative predictive value, PPV positive predictive value, TN Tibial nerve