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Table 4 Quantitative ROC curve analysis cutoff values for tibial nerve CSA and stiffness between patients with DPN and control/DM groups to detect diabetic peripheral neuropathy

From: Diagnostic value of shear wave ultrasound elastography of tibial nerve in patients with diabetic peripheral neuropathy

Variable

Mean Stiffness value (at cutoff = 86.5 kPa)

CSA by US (at cutoff = 14.5 mm2)

Control/DM group (n = 200 TN)

56.16 ± 21.39

10.71 ± 2.04

DPN group (n = 100 TN)

97.94 ± 19.55

16.72 ± 1.89

P value

< 0.001

0.074

Sensitivity (%)

94.6

71

Specificity (%)

93.8

69

AUC (area under curve)

0.975

0.671

NPV (%)

95

64.5

PPV (%)

93

67.8

  1. CSA cross−sectional area, DM Diabetes mellitus, DPN Diabetic peripheral neuropathy, kPa kilopascals, NPV Negative predictive value, PPV positive predictive value, TN Tibial nerve