Egyptian Journal of Radiology and Nuclear Medicine

Table 3 Accuracy, sensitivity, specificity, PPV, NPV of sonographic parameters

From: Evaluation of sensitivity and accuracy of maternal serum alpha fetoprotein to the diagnosis of open spina bifida in comparison with sonographic findings of open spina bifida and Chiari II malformation in pregnant women

	OSB
	Positive	Negative	Accuracy	Sensitivity	Specifity	PPV	NPV
Rised AFP
Positive	4	51	0.073	0.073	–	1.00	0.00
Negative	0	0
Normal IT
Positive	0	51	1.00	1.00	1.00	1.00	1.00
Negative	4	0
Decreased CM
Positive	4	0	1.00	1.00	1.00	1.00	1.00
Negative	0	51
Increased BS
Positive	2	0	1.00	1.00	1.00	1.00	1.00
Negative	0	51
Decreased BSOB
Positive	2	0	1.00	1.00	1.00	1.00	1.00
Negative	0	51
Increased BS/BSOB
Positive	2	0	1.00	1.00	1.00	1.00	1.00
Negative	0	51
BPD decrease
Positive	0	0	0.927	–	0.927	0.00	1.00
Negative	4	51
Ventriculomegalia
Positive	2	2	0.945	0.667	0.962	0.5	0.98
Negative	1	50

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