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Table 3 Accuracy, sensitivity, specificity, PPV, NPV of sonographic parameters

From: Evaluation of sensitivity and accuracy of maternal serum alpha fetoprotein to the diagnosis of open spina bifida in comparison with sonographic findings of open spina bifida and Chiari II malformation in pregnant women

  OSB
Positive Negative Accuracy Sensitivity Specifity PPV NPV
Rised AFP        
Positive 4 51 0.073 0.073 1.00 0.00
Negative 0 0      
Normal IT        
Positive 0 51 1.00 1.00 1.00 1.00 1.00
Negative 4 0      
Decreased CM        
Positive 4 0 1.00 1.00 1.00 1.00 1.00
Negative 0 51      
Increased BS        
Positive 2 0 1.00 1.00 1.00 1.00 1.00
Negative 0 51      
Decreased BSOB        
Positive 2 0 1.00 1.00 1.00 1.00 1.00
Negative 0 51      
Increased BS/BSOB        
Positive 2 0 1.00 1.00 1.00 1.00 1.00
Negative 0 51      
BPD decrease        
Positive 0 0 0.927 0.927 0.00 1.00
Negative 4 51      
Ventriculomegalia        
Positive 2 2 0.945 0.667 0.962 0.5 0.98
Negative 1 50