Table 1 Diagnostic performance of the T1 and T2 Dixon modalities
From: Dixon chemical shift MR sequences for demonstrating of bone marrow vertebral metastasis
Measure | T2 Dixon (WO) | T2 Dixon (OP) | T1 post-contrast Dixon (WO) | T1 and T2 Dixon (FO) | T1 post-contrast Dixon (OP) |
|---|---|---|---|---|---|
True positive | 126 | 126 | 149 | 144 | 133 |
True negative | 21 | 21 | 21 | 21 | 21 |
False positive | 0 | 0 | 0 | 0 | 0 |
False negative | 35 | 35 | 12 | 17 | 27 |
Sensitivity | 78.3% (71.1%–84.4%) | 78.3% (71.1%–84.4%) | 92.6% (87.3%–96.1%) | 89.4% (83.6%–93.7%) | 83.1% (76.4%–88.6%) |
Specificity | 100% (83.9%–100%) | 100% (83.9%–100%) | 100% (83.9%–100%) | 100% (83.9%–100%) | 100% (83.9%–100%) |
PPV | 100% | 100% | 100% | 100% | 100% |
NPV | 37.5% (30.9%–44.6%) | 37.5% (30.9%–44.6%) | 63.6% (50.4%–75.1%) | 55.3% (44.1%–65.9%) | 43.8% (35.5%–52.3%) |
LR- | 21.7% (16.2%–29.1%) | 21.7% (16.2%–29.1%) | 7.5% (4.3%–12.8%) | 10.6% (6.7%–16.6%) | 16.9% (12%–23.8%) |
Accuracy | 80.8% (74.3%–86.2%) | 80.8% (74.3%–86.2%) | 93.4% (88.8%–96.5%) | 90.7% (85.5%–94.5%) | 85.1% (79%–89.9%) |
F1 score | 87.8% | 87.8% | 96.1% | 94.4% | 90.8% |
MCC | 54.2% | 54.2% | 76.7% | 70.3% | 60.3% |
AUC | 0.891 (0.837–0.933) | 0.891 (0.837–0.933) | 0.963 (0.924–0.985) | 0.947 (0.904–0.975) | 0.916 (0.865–0.952) |