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Table 1 Nottingham combined histological grade, Ref [11]

From: Value of apparent diffusion coefficient factor in correlation with the molecular subtypes, tumor grade, and expression of Ki-67 in breast cancer

Feature graded Criterion Score
Tubule(graded) formation  > 75% 1
10–75% 2
 < 10% 3
Nuclear pleomorphism Small, regular uniform cells 1
Moderate increase and variablity 2
Marked variation 3
Mitotic count (/10 hpf) 0–5 1
6–10 2
 > 11 3