Table 3 MRI features correlation with molecular markers
Molecular markers | Test of Sig | p | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Luminal A (n = 37) | Luminal B HER2-negative (n = 19) | Luminal B HER2-positive (n = 12) | HER2-amplified (n = 4) | Triple-negative (n = 8) | ||||||||
No | % | No | % | No | % | No | % | No | % | |||
Age (years) | ||||||||||||
< 50 | 18 | 48.6 | 8 | 42.1 | 6 | 50.0 | 1 | 25.0 | 1 | 12.5 | χ2 = 4.195 | MCp = 0.395 |
≥ 50 | 19 | 51.4 | 11 | 57.9 | 6 | 50.0 | 3 | 75.0 | 7 | 87.5 | ||
Min.–Max | 38.0–66.0 | 43.0–70.0 | 37.0–77.0 | 46.0–68.0 | 47.0–75.0 | F = 1.879 | 0.123 | |||||
Mean ± SD | 50.41 ± 7.21 | 53.21 ± 8.06 | 54.92 ± 12.89 | 57.0 ± 9.13 | 58.13 ± 8.71 | |||||||
Median | 50.0 | 52.0 | 51.50 | 57.0 | 56.0 | |||||||
Menstrual status | ||||||||||||
Premenopausal | 18 | 48.6 | 8 | 42.1 | 6 | 50.0 | 1 | 25.0 | 1 | 12.5 | χ2 = 4.195 | MCp = 0.395 |
Postmenopausal | 19 | 51.4 | 11 | 57.9 | 6 | 50.0 | 3 | 75.0 | 7 | 87.5 | ||
Clinical presentation | ||||||||||||
Asymptomatic | 6 | 16.2 | 0 | 0.0 | 1 | 8.3 | 0 | 0.0 | 0 | 0.0 | χ2 = 4.105 | MCp = 0.288 |
Symptomatic | 31 | 83.8 | 19 | 100.0 | 11 | 91.7 | 4 | 100.0 | 8 | 100.0 | ||
Parity | ||||||||||||
Nullipara | 6 | 16.2 | 8 | 42.1 | 2 | 16.7 | 1 | 25.0 | 1 | 12.5 | χ2 = 5.239 | MCp = 0.233 |
Multipara | 31 | 83.8 | 11 | 57.9 | 10 | 83.3 | 3 | 75.0 | 7 | 87.5 | ||
Histological type | ||||||||||||
IDC | 34 | 91.9 | 19 | 100.0 | 10 | 83.3 | 4 | 100.0 | 8 | 100.0 | χ2 = 12.125 | MCp = 0.625 |
ILC | 2 | 5.4 | 0 | 0.0 | 1 | 8.3 | 0 | 0.0 | 0 | 0.0 | ||
DCIS | 0 | 0.0 | 0 | 0.0 | 1 | 8.3 | 0 | 0.0 | 0 | 0.0 | ||
Mucinous | 1 | 2.7 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | ||
Grading of IDC | ||||||||||||
I | 0 | 0.0 | 1 | 5.3 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | χ2 = 10.044 | MCp = 0.265 |
II | 12 | 35.3 | 5 | 26.3 | 2 | 20.0 | 0 | 0.0 | 0 | 0.0 | ||
III | 22 | 64.7 | 13 | 68.4 | 8 | 80.0 | 4 | 100.0 | 8 | 100.0 | ||