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Table 6 MR imaging pattern for extra sinus extension

From: Magnetic resonance imaging features of post-COVID-19 regional and invasive sino-nasal mucormycosis

Pattern of extra-sinus extension

N (%)

MRI features

Maxilla-facial soft-tissue

Pre-antral soft tissue

43 (69.35)

Infiltration of the implicated soft-tissue spaces with fat stranding was primarily seen on T1 W, T2 W, fat-saturated T2W and postcontrast T1W images

Retro-antral fat

33 (53.23)

Pterygopalatine fossa

47 (75.8)

Infra-temporal fossa

22 (35.48)

Pre-septal space

30 (48.39)

Buccal space

5 (8.06)

Maxillo-facial bones

Anterior maxillary and zygomatic bone

2 (3.23)

Marrow edema and enhancement of the affected bones manifested primarily in fat-saturated T2W and postcontrast T1W images, respectively

Maxillary process of palatine bone

6 (9.68)

Orbit

Intraorbital intra-conal fat

12 (19.35)

T1W, fat-saturated T2W, and postcontrast T1W images showed retrobulbar fat stranding/edema and enhancing soft tissue in the orbit with or without extraocular muscle involvement

Intraorbital intra-conal soft tissue extension

8 (12.9)

Including extra-ocular muscles

7 (11.29)

Orbital apex

6 (9.68)

Optic nerve

5 (8.06)

Optic nerve infarction is indicated by diffusion restriction within the nerve

Skull base

5 (8.06)

Bone marrow signal changes at the affected Clivus and pterygoid bones, along with marrow edema and enhancement, were most noticeable in fat-saturated T2W and postcontrast T1W images, respectively

Intracranial

Cavernous sinus thrombosis

5 (8.06)

Abnormal signal intensity of the affected cavernous sinus, with abnormal enhancement, manifested mainly in fat-saturated T2W and postcontrast T1W images

ICA narrowing/occlusion

3 (4.84)

MR angiography and postcontrast T1W images demonstrated internal carotid artery constriction without or with arterial wall enhancement

Epidural/subdural collections

4 (6.45)

Epidural/sub-dural collections, with meningeal enhancement

Focal cerebritis

3 (4.84)

Cerebral parenchymal signal alterations with peripheral enhancement appreciated in T2W, diffusion-weighted and postcontrast T1W images indicating cerebral parenchymal invasion/abscess development

Cerebral infarction

3 (4.84)

Cortical and subcortical T2 and FLAIR hyperintense area with restricted diffusion following the vascular territory or in the watershed area indicating acute infarction