Updating the role of transcranial Doppler in prediction and prevention of stroke in correlation to the regularity of blood transfusion in Egyptian children with sickle cell anemia

Egyptian Journal of Radiology and Nuclear Medicine

Table 4 Comparison between groups according to risk of stroke regarding demographic, hematological, biochemical and radiological parameters

	Low risk (n = 63)	Conditional (n = 3)	High risk (n = 3)	P value
Age of onset (months) (mean ± SD)	12.84 ± 13.51	24 ± 12	36 ± 0.18	0.008
Plt	344.49 ± 120.56	270 ± 146.54	155 ± 0.41	0.022
Bil T	2.03 ± 1.07	2.83 ± 0.86	3.60 ± 0.34	0.025
Bil D	0.36 ± 0.18	0.79 ± 0.41	1.20 ± 0.74	0.000
Peak Systolic Velocity (cm/s)
Rt MCA	140.61 ± 27.52	178.33 ± 24.70	182 ± 9.14	0.004
Lt MCA	145 ± 33.06	186.33 ± 21.12	206 ± 3.10	0.002
Rt DICA	134.92 ± 37.36	145.33 ± 40.45	161 ± 3.38	0.875
Lt DICA	117.04 ± 35.17	169.33 ± 49.05	172 ± 2.27	0.003
Rt ACA	127.88 ± 26.37	162.66 ± 85.57	240 ± 5.24	0.000
Lt ACA	123.38 ± 33.04	210.66 ± 91.06	307 ± 0.98	0.000
Rt PCA	117.76 ± 40.42	155.33 ± 75.63	198 ± 8.03	0.004
Lt PCA	115.92 ± 46.83	164.66 ± 31.65	168 ± 0.04	0.109
TA max	Time average mean of maximum velocity (cm/s)
Rt MCA	96.69 ± 21.34	127.33 ± 19.5	137 ± 5.2	0.005
Lt MCA	89.28 ± 29.73	128.33 ± 16.5	145 ± 0.74	0.001
Rt DICA	94.25 ± 22.31	109.33 ± 3.89	127.25 ± 0.07	0.523
Lt DICA	82.34 ± 23.22	131.33 ± 53.37	154 ± 0.35	0.000
Rt ACA	88.40 ± 19.56	120.33 ± 63.06	185 ± 1.23	0.000
Lt ACA	85.69 ± 23.59	145.33 ± 49.81	224 ± 14.78	0.000
Rt PCA	82.84 ± 26.10	108.33 ± 52.04	146 ± 17.25	0.001
Lt PCA	78.94 ± 30.30	112.33 ± 12.34	122 ± 12.14	0.084

Bil Bilirubin, Rt right, Lt Left, MCA middle cerebral artery, DICA distal internal carotid artery, ACA anterior cerebral artery, PCA posterior cerebral artery