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Egyptian Journal of Radiology and Nuclear Medicine
Fig. 3 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 3

From: Suspicious lung lesions for malignancy: the lesion-to-spinal cord signal intensity ratio in T2WI and DWI–MRI versus PET/CT; a prospective pathologic correlated study with accuracy and ROC analyses

Fig. 3

A 24-year-old female patient complained of chronic cough and dyspnea. A Axial contrast-enhanced chest CT cut (mediastinal window) showed bilateral hilar and posterior mediastinal sub-carinal nodal enlargement. B Coronal chest PET-CT image showing high 18F-FDG uptake at thoracic, bilateral supra-clavicular, and left cervical nodal enlargement. C, D Axial T2WI showing the high signal intensity of bilateral nodal and parenchymal masses. After placing two ROIs within the largest lesion and the spinal cord, the lesion-to-spinal cord signal intensity ratio was calculated = 1.4. E Axial DWI showing bright signal of restricted diffusion and lesion-to-spinal cord signal intensity ratio was calculated = 0.8. F ADC mapping images showing low signal intensity with minimum ADC (1 × 10−3 mm2/s) and mean ADC (1.3 × 10−3 mm2/s). Referring to the estimated cutoff values, T2WI L-to-SC SI ratio, DWI L-to-SC SI ratio, minimum ADC, and mean ADC suggested a malignant process. Pathologically proven large cell lymphoma

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