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Fig. 3 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 3

From: Relationships of 18F-FDG PET with tumor microenvironment immunotypes, especially PD-L1 and CD15 expression, and prognosis in oral squamous cell carcinoma

Fig. 3

A Patients were classified into four groups (A–D) based on programmed death ligand-1 (PD-L1) expression in tumor cells and CD15+ cell counts at the tumor invasive front. B Box-and-whisker diagrams present fluoro-d-glucose (FDG) uptake in the four subgroups. Group C (low PD-L1 expression and low density of CD15+ cells) had significantly lower FDG uptake (indicated by the maximum standardized uptake value [SUVmax]) than group B (P = 0.04). C Kaplan–Meier plots of relapse-free survival in the subgroups. Group C had significantly better survival than groups A and D (P = 0.005 and P = 0.009, respectively) (high PD-L1 expression and high density of CD15+ cells)

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