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Table 9 Diagnostic features of HEART and Coronary artery calcium SCOREs cut points in diagnosing abnormal Multislice CT coronary angiography grades

From: Multislice CT coronary angiography and coronary artery calcium scoring, correlation with Heart Score

Characteristics

HEARTSCORE ≥ 2.0

HEARTSCORE ≥ 8.0

CACS ≥ 6.0

Value

95% CI

Value

95% CI

Value

95% CI

Sensitivity

95.2%

86.7%–99.0%

47.6%

34.9%–60.6%

85.7%

74.6%–93.3%

Specificity

45.9%

29.5%–63.1%

97.3%

85.8%–99.9%

89.2%

74.6%–97.0%

DA

77.0%

67.5%–84.8%

66.0%

55.8%–75.2%

87.0%

78.8%–92.9%

YI

41.2%

24.3%–58.1%

44.9%

31.5%–58.3%

74.9%

61.7%–88.1%

PPV

75.0%

64.1%–84.0%

96.8%

83.3%–99.9%

93.1%

83.3%–98.1%

NPV

85.0%

62.1%–96.8%

52.2%

39.8%–64.4%

78.6%

63.2%–89.7%

LR + 

1.76

1.30–2.38

17.62

2.51–123.91

7.93

3.13–20.11

LR-

0.10

0.03–0.33

0.54

0.42–0.69

0.16

0.09–0.30

DOR

17.00

4.51–64.12

32.73

4.22–253.61

49.50

14.11–173.62

  1. Bold-underline: A p-value less than 0.05 (typically ≤ 0.05) is statistically significant
  2. CI: Confidence interval. DA: Diagnostic accuracy. YI: Youden's index PPV: Positive Predictive value. NPV: Negative Predictive value. LR + : Positive likelihood ratio. LR-: Negative likelihood ratio. DOR: Diagnostic odds ratio