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Egyptian Journal of Radiology and Nuclear Medicine
Fig. 7 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 7

From: Quantitative mathematical objective evaluation of contrast-enhanced spectral mammogram in the assessment of response to neoadjuvant chemotherapy and prediction of residual disease in breast cancer

Fig. 7

A 47-year-old patient with IDC of the right breast. Biomarker status of the tumor was ER-positive, PR-positive, and HER-2 positive. a Pre NAC mammogram MLO view showing right breast UOQ speculated mass with micro-calcific clusters. b Post NAC mammogram MLO view showing mild decrease of the size of the mass. c Pre NAC CESM MLO view separated lesions; multi-centric masses. d Post NAC CESM CC view showing residual multi-nodular lesions. e Quantitative mathematical objective evaluation showed 84% percentage of regression. Combined evaluation response classified this patient as moderate response with 30–60% decrease in longest dimension of the dominant mass and decrease in intensity (partial responder). RECIST 1.1 classified her as partial responder. Pathological evaluation confirmed this patient as a pathological responder (Miller–Payne grade 3)

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