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Table 1 The combined evaluation response approach

From: Quantitative mathematical objective evaluation of contrast-enhanced spectral mammogram in the assessment of response to neoadjuvant chemotherapy and prediction of residual disease in breast cancer


Tumor largest diameter

Intensity of enhancement

• Progressive disease


+/− change in the intensity

• Stable disease

No change in size

No change

• Poor response

Up to 30% decrease

Decrease in intensity

• Moderate response

30–60% decrease

Decrease in intensity

• Marked response

> 60% decrease

Residual faint enhancement

• Complete Response

No residual lesion seen