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Table 4 ROC curve analysis of DTI/FA values for discrimination of occurrence of cerebral palsy

From: Can diffusion tensor imaging predict cerebral palsy in term neonates with hypoxic ischemic encephalopathy?

Index

AUC (95% CI)

Z (p value)

Cutoff value(YI)

Sensitivity (95% CI)

Specificity (95% CI)

PPV (%)

NPV (%)

Centrum semiovale

0.949 (0.811–0.995)

9.275 (< 0.0001*)

≤ 0.235

93.75 (69.8–99.8)

94.12 (71.3–99.9)

93.7

94.1

PLIC

1.000 (0.894–1.000)

0 (< 0.0001*)

≤ 0.435

100.00 (79.4–100.0)

100.00 (80.5–100.0)

100.0

100.0

OWM

0.581 (0.397–0.750)

0.789 (0.4303 NS)

     

OR

0.511 (0.332–0.688)

0.103 (0.9182 NS)

     

Genu of CC

0.811 (0.637–0.925)

4.107 (< 0.0001*)

≤ 0.45

56.25 (29.9–80.2)

100.00 (80.5–100.0)

100.00

70.8

Splenium of CC

0.814 (0.637–0.929)

3.911 (< 0.0001*)

≤ 0.45

60.00 (32.3–83.7)

100.00 (80.5–100.0)

100.0

73.9

  1. AUC area under the curve, CC corpus callosum, CI confidence interval, NPV negative predictive value, OR optic radiation, OWM occipital white matter, PLIC posterior limb of internal capsule, PPV positive predictive value, NS statistically not significant (p > 0.05)
  2. *Statistically significant (p < 0.05)