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Table 2 The performance of FA and MD in assessing cerebral white matter integrity

From: Diffusion tensor imaging of white matter integrity in relation to smoking index and exacerbations in severe chronic obstructive pulmonary disease

 AUC95% CICut off pointSensitivity (%)Specificity (%)PPV (%)NPV (%)Accuracy (%)
FA
 SLF.853.74–.96.370576.7%73.3%85.2%73.3%75.5%
 IOFF.892.80–.98.399580%73.3%85.7%73.3%77.8%
 UF.896.80–.98.324580%73.3%85.7%73.3%77.8%
 CING.912.83–.99.344583.3%73.3%86.2%68.7%80%
 OR.897.80–.98.399083.3%73.3%86.2%68.7%80%
 GCC.840.72–.95.582573.3%73.3%84.6%57.9%73.3%
 SCC.893.79–.99.590076.7%73.3%85.2%73.3%75.5%
MD
 SLF.991.97–1.0.894096.7%86.7%93.5%92.8%93.3%
 IOFF.987.96–1.0.902093.3%86.7%93.3%86.7%91.1%
 UF.980.94–1.0.958093.3%86.7%93.3%86.7%91.1%
 CING.996.98–1.0.9145100%86.7%93.7%100%95.5%
 OR.923.84–1.0.927583.3%86.7%92.6%72.2%84.4%
 GCC.899.81–.98.886580%86.7%92.3%68.4%82.2%
 SCC.931.85–1.0.868090%86.7%93.1%81.2%88.9%
  1. Footnotes: AUC area under the curve, CI confidence interval, PPV positive predictive value, NPV negative predictive value