Table 2 The performance of FA and MD in assessing cerebral white matter integrity
AUC | 95% CI | Cut off point | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | |
|---|---|---|---|---|---|---|---|---|
FA | ||||||||
SLF | .853 | .74–.96 | .3705 | 76.7% | 73.3% | 85.2% | 73.3% | 75.5% |
IOFF | .892 | .80–.98 | .3995 | 80% | 73.3% | 85.7% | 73.3% | 77.8% |
UF | .896 | .80–.98 | .3245 | 80% | 73.3% | 85.7% | 73.3% | 77.8% |
CING | .912 | .83–.99 | .3445 | 83.3% | 73.3% | 86.2% | 68.7% | 80% |
OR | .897 | .80–.98 | .3990 | 83.3% | 73.3% | 86.2% | 68.7% | 80% |
GCC | .840 | .72–.95 | .5825 | 73.3% | 73.3% | 84.6% | 57.9% | 73.3% |
SCC | .893 | .79–.99 | .5900 | 76.7% | 73.3% | 85.2% | 73.3% | 75.5% |
MD | ||||||||
SLF | .991 | .97–1.0 | .8940 | 96.7% | 86.7% | 93.5% | 92.8% | 93.3% |
IOFF | .987 | .96–1.0 | .9020 | 93.3% | 86.7% | 93.3% | 86.7% | 91.1% |
UF | .980 | .94–1.0 | .9580 | 93.3% | 86.7% | 93.3% | 86.7% | 91.1% |
CING | .996 | .98–1.0 | .9145 | 100% | 86.7% | 93.7% | 100% | 95.5% |
OR | .923 | .84–1.0 | .9275 | 83.3% | 86.7% | 92.6% | 72.2% | 84.4% |
GCC | .899 | .81–.98 | .8865 | 80% | 86.7% | 92.3% | 68.4% | 82.2% |
SCC | .931 | .85–1.0 | .8680 | 90% | 86.7% | 93.1% | 81.2% | 88.9% |