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Table 4 Correlation between clinical data and volumetric data of different brain structures

From: Voxel-based morphometry in patients with mood disorder bipolar I mania in comparison to normal controls

 Age (years)No. of attacksDuration of illnessAge of onset (years)Duration of last episodeYoung Mania Rating scale
Rt caudate
r value−0.4200.0510.108−0.441− 0.0580.373
p value0.041*0.8120.6150.031*0.7890.072
Lt caudate
r value− 0.3600.0860.098−0.351− 0.1840.384
p value0.0840.6900.6490.0930.3910.064
Rt putamen
r value−0.621− 0.220− 0.223− 0.4650.331− 0.004
p value0.001**0.3020.2950.022*0.1140.986
Lt putamen
r value−0.606− 0.195− 0.262− 0.4160.2600.090
p value0.002**0.3600.2150.043*0.2210.677
Rt thalamus
r value−0.119− 0.0450.008− 0.125− 0.2810.407
p value0.5780.8330.9720.5600.1840.049**
Lt thalamus
r value−0.091−0.127−0.034− 0.091−0.3620.581
p value0.6720.5550.8760.6710.0820.003**
Rt globus pallidus
r value−0.552−0.329−0.384− 0.3410.310− 0.295
p value0.005*0.1170.0640.1030.1400.162
Lt globus pallidus
r value−0.437−0.141−0.166− 0.4600.159− 0.064
p value0.033*0.5120.4390.024*0.4580.768
Rt hippocumpus
r value−0.155−0.229−0.3090.123−0.0620.307
p value0.4700.2820.1410.5670.7750.145
Lt hippocumpus
r value−0.186−0.029−0.167− 0.0830.0600.465
p value0.3840.8910.4350.7000.7790.022*
Rt amygdala
r value−0.132−0.471−0.2510.0730.032−0.091
p value0.5400.020*0.2370.7350.8820.672
Lt amygdala
r value−0.152−0.192−0.145− 0.046−0.2540.139
p value0.4780.3690.4980.8310.2310.516
Rt cerebral hemisphere
r value−0.434−0.157−0.189− 0.336−0.2140.472
p value0.034*0.4650.3770.1080.3150.020*
Lt cerebral hemisphere
r value−0.451−0.130−0.218− 0.330−0.1900.484
p value0.027*0.5450.3070.1150.3730.016*
Rt lateral ventricle
r value−0.388−0.250−0.4870.007*0.101−0.198
p value0.0610.2390.016*0.9730.6400.353
Lt lateral ventricle
r value−0.378−0.207−0.384− 0.0440.037− 0.283
p value0.0690.3310.0640.8390.8640.180
Rt cerebral gray matter
r value−0.633−0.498−0.470− 0.2690.0170.080
p value0.001**0.013*0.021*0.2040.9380.711
Lt cerebral gray matter
r value−0.626−0.462−0.492− 0.238−0.0060.107
p value0.001**0.023*0.015*0.2630.9790.620
Rt cerebral white matter
r value0.0170.1440.096−0.006−0.4040.685
p value0.9360.5010.6560.9790.0500.000*
Lt cerebral white matter
r value−0.0190.1110.022−0.015−0.4220.651
p value0.9290.6050.9200.9430.040*0.001*
Rt cerebellar hemisphere
r value−0.174−0.256−0.1750.065−0.3130.091
p value0.4170.2270.4120.7620.1370.674
Lt cerebellar hemisphere
r value−0.262−0.275−0.2690.046−0.2360.151
p value0.2160.1930.2040.8300.2660.482
  1. Rt right, Lt left
  2. * Significant; ** highly significant