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Table 4 Diagnostic value of the variables according to grade subgroups

From: Perfusion and permeability MRI in glioma grading

 Predictive ValueSensitivitySpecificityPPVNPVAUCp
High grade (ref: low)
 rCBV> 3.25100.00100.00100.0100.01.000< 0.001*
 rCBF> 3.22100.00100.00100.0100.01.000< 0.001*
 Ktans> 0.04381.82100.00100.022.40.962< 0.001
 Ve> 0.255100.00100.00100.0100.01.000< 0.001*
Grade 3 (ref: 1, 2)
 rCBV> 3.25100.00100.00100.0100.01.000< 0.001*
 rCBF> 3.22100.00100.00100.0100.01.000< 0.001*
 Kttrans> 0.03892.8681.2598.937.40.940< 0.001*
 Ve> 0.255100.00100.00100.0100.01.000< 0.001*
Grade 4 (ref: 1, 2)
 rCBV> 5.67100.0092.8699.6100.00.991< 0.001*
 rCBF> 5.44100.00100.00100.0100.01.000< 0.001*
 Ktrans> 0.11175.0085.7099.015.30.853< 0.001*
 Ve> 0.4987.5078.5798.724.90.884< 0.001*
  1. *p < 0.05 statistical significance
  2. PPV positive predictive value, NPV negative predictive value, AUC area under curve