Perfusion and permeability MRI in glioma grading

Egyptian Journal of Radiology and Nuclear Medicine

Table 4 Diagnostic value of the variables according to grade subgroups

	Predictive Value	Sensitivity	Specificity	PPV	NPV	AUC	p
High grade (ref: low)
rCBV	> 3.25	100.00	100.00	100.0	100.0	1.000	< 0.001*
rCBF	> 3.22	100.00	100.00	100.0	100.0	1.000	< 0.001*
Ktans	> 0.043	81.82	100.00	100.0	22.4	0.962	< 0.001
Ve	> 0.255	100.00	100.00	100.0	100.0	1.000	< 0.001*
Grade 3 (ref: 1, 2)
rCBV	> 3.25	100.00	100.00	100.0	100.0	1.000	< 0.001*
rCBF	> 3.22	100.00	100.00	100.0	100.0	1.000	< 0.001*
Kttrans	> 0.038	92.86	81.25	98.9	37.4	0.940	< 0.001*
Ve	> 0.255	100.00	100.00	100.0	100.0	1.000	< 0.001*
Grade 4 (ref: 1, 2)
rCBV	> 5.67	100.00	92.86	99.6	100.0	0.991	< 0.001*
rCBF	> 5.44	100.00	100.00	100.0	100.0	1.000	< 0.001*
Ktrans	> 0.111	75.00	85.70	99.0	15.3	0.853	< 0.001*
Ve	> 0.49	87.50	78.57	98.7	24.9	0.884	< 0.001*

*p < 0.05 statistical significance
PPV positive predictive value, NPV negative predictive value, AUC area under curve