Table 4 Neurodevelopmental outcome in PCMs
| Â | No. cases/% | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
PCMs | GDD | Motor delay | Language delay | Intellectual disability | ASD | ADHD | Epilepsy | Ataxic gait | Nystagmus | Tremors | Behavioral changes |
Cerebellar hypoplasia (unknown diagnosis) (n = 29) | 27 | 21 | 16 | 14 | 0 | 0 | 19 | 6 | 0 | 2 | 3 |
Isolated vermian hypoplasia (n = 4) | 2 | 2 | 4 | 3 | 3 | 2 | 3 | 0 | 0 | 1 | 1 |
Dandy-Walker malformation (DWM) (n = 14) | 12 | 6 | 7 | 8 | 5 | 5 | 3 | 7 | 0 | 3 | 0 |
Congenital disorders of glycosylation (n = 4) | 4 | 2 | 3 | 2 | 1 | 1 | 2 | 4 | 4 | 1 | 1 |
Congenital muscular dystrophy (n = 3) | 3 | 3 | 3 | 3 | 0 | 0 | 2 | 2 | 3 | 1 | 0 |
Lhermitte-Duclos Cowden Syndrome (n = 1) | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Rhomboencephalosynapsis (n = 2) | 2 | 1 | 2 | 2 | 1 | 1 | 0 | 2 | 2 | 0 | 1 |
DWM with Joubert syndrome (n = 1) | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Total (n = 58) | 52/ 90% | 37/ 64% | 37/ 64% | 34/ 59% | 10/ 17% | 11/ 19% | 31/ 53% | 33/ 57% | 9/ 15% | 9/ 15% | 6/ 7% |