COVID-19 disease: CT Pneumonia Analysis prototype by using artificial intelligence, predicting the disease severity

Egyptian Journal of Radiology and Nuclear Medicine

Table 2 Quantitative parameters at different clinical groups

Parameters	Clinical score			P value	Post hoc
Parameters	A (n = 32), mean ± SD	B (n = 56), mean ± SD	C (n = 32), mean ± SD	P value	Post hoc
Total opacity score	5.81 ± 2.64	10.92 ± 3.77	17.00 ± 2.59	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Lung volume	3512.89 ± 1165	2874.89 ± 873.80	2257.30 ± 608.25	< 0.001	P1 0.028 P2 < 0.001 P3 0.001
LAV	− 611.34 ± 156.72	− 538.67 ± 80.33	− 483.62 ± 74.87	< 0.001	P1 0.056 P2 < 0.001 P3 0.006
HAV	− 396.44 ± 183.77	− 311.10 ± 89.04	− 260.98 ± 67.69	< 0.001	P1 0.053 P2 0.012 P3 < 0.001
Percentage of opacity	14.73 ± 12.83	40.51 ± 21.19	73.75 ± 15.75	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Volume of opacity	460.38 ± 331.83	1079.76 ± 469.84	1681.01 ± 562.28	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Volume of high opacity	98.40 ± 79.74	314.84 ± 124.39	564.70 ± 192.39	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Percentage of high opacity	3.30 ± 3.14	12.32 ± 7.47	25.52 ± 7.50	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Mean HU total (MLD)	− 710.59 ± 91.50	− 593.10 ± 93.75	− 435.77 ± 88.19	< 0.001	P1 < 0.001 P2 < 0.001 P3 < 0.001
Mean HU of opacity	− 489.42 ± 120.72	− 386.66 ± 86.71	− 352.08 ± 60.09	< 0.001	P1 < 0.001 P2 < 0.001 P3 0.089

P1 mild vs moderate, P2 mild vs severe, P3 moderate vs severe, HAV high attenuation value, LAV low attenuation value, MLD mean lung density