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Egyptian Journal of Radiology and Nuclear Medicine
Fig. 5 | Egyptian Journal of Radiology and Nuclear Medicine

Fig. 5

From: Diffusion-weighted magnetic resonance imaging (DWMRI) of head and neck squamous cell carcinoma: could it be an imaging biomarker for prediction of response to chemoradiation therapy

Fig. 5

A 59-year-old male patient with right sided stage IVA transglottic laryngeal SCC (T4aN0M0) treated by concomitant chemoradiotherapy. a–e Axial pretreatment MR images. a T2WI with fat suppression, b non-contrast T1WI, c post-GAD T1WI with fat suppression, d b-1000 TSE-DWI, e the corresponding ADC map, all showed moderately hyperenhancing T2 hyperintense right-sided transglottic soft tissue mass with restricted diffusion (ADC = 1 × 10−3 mm2/s). f–h Axial midtreatment MR images performed 3 weeks after start of chemoradiotherapy. f T2WI with fat suppression, g b-1000 TSE-DWI, h the ADC map, all showed mild progression in size of the tumor. DWI did not show ADC rise (ADC = 1 × 10−3 mm2/s). i Axial T2WI 5 weeks after end of CRT revealed suspicious residual tumor (black arrow). j–l Further axial MR images performed 5 months after end of treatment. j T2WI, k high b value DWI, l the corresponding ADC map showed marked progression in size of the residual mass with restricted diffusion (ADC = 0.95 × 10−3 mm2/s), confirming its neoplastic nature and treatment failure

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