Fig. 3
From: Arterial spin labeling in the grading of brain gliomas: could it help?
MR perfusion in a case with the right frontal high-grade glioma. a Axial T2WI showing right frontal hyperintense signal sizable lesion. b, c Pre- and post contrast T1WI showing hypointense signal with patchy faint post contrast enhancement. d ASL-CBF showing a high perfusion of the lesion with ASL-rCBF value of 8.03. e, f DSC-CBF and CBV showing a high perfusion with DSC-rCBF value of 4.16 and DSC-rCBV value of 8.16. g Hematoxylin and eosin staining (×400 magnification) showing increased cellularity with vascular proliferation (arrows), palisading necrosis and marked cellular atypia, pathologically proven glioblastoma, NOS WHO grade IV with ASL matching with DSC in showing hyperperfusion of the lesion. ASL arterial spin labeling, CBF cerebral blood flow, DSC dynamic susceptibility contrast, CBV cerebral blood volume, NOS not otherwise specified, r relative, WI weighted imaging