Fig. 2
From: The role of diffusion-weighted MRI in assessment of response to chemotherapy in osteosarcoma
A 22-year-old male with osteosarcoma in the left proximal tibia. MR images a–c before and d–f after chemotherapy. a, b Axial T2-WI and contrast-enhanced T1-WI showing left upper tibial intra medullary infiltrative lesion associated with extra osseous soft tissue component. It elicits high T2 signal and heterogeneous post contrast enhancement with areas of necrosis and cystic degeneration. c ADC map revealed patchy diffusion restriction of the lesion with mean ADC value (mean, 0.86 × 10−3 mm2/s). d, e Follow-up axial T2-WI and contrast-enhanced T1-WI showing slight size regression with less contrast uptake. f Follow-up ADC map showing elevated ADC values (mean, 1.68 × 10−3 mm2/s) denoting good therapeutic response