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Table 1 Patients and tumor characteristic according to BAT status

From: Brown adipose tissue (BAT) activation at 18F-FDG PET/CT: correlation with clinicopathological characteristics in breast cancer

Parameter BAT 18F-FDG uptake P value
Positive (n=16) Negative (n=141)
Outdoor temperature:    
• Median (IQR) 26 (12) 34 (15) 0.035b
Age:
• <50 years 14 (87.5%) 64 (45.4%) 0.001a
• ≥50 years 2 (12.5%) 77 (54.6%)
BMI: 0.001a
• < 25 10 (62.5%) 32 (22.7%)
• ≥ 25 6 (37.5%) 109 (77.3%)
Tumor size in cm 0.680b
• Median (IQR) 2.5 (0.9) 2.7 (1.8)
Primary SUVmax 0.979b
• Median (IQR) 5.92 (11.96) 8.2 (9.21)
ER status: 0.668a
• Positive 11 (68.6%) 104 (73.8%)
• Negative 5 (31.2%) 37 (26.2%)
PR status: 0.783a
• Positive 10 (62.5%) 93 (66%)
• Negative 6 (37.5%) 48 (34%)
HER2neu: 0.356a
• Positive 5 (31.2%) 61 (43.3%)
• Negative 11 (68.8%) 80 (56.7%)
Histology : 0.937a
• IDC 14 (87.5%) 124 (87.9%)
• ILC 2 (12.5%) 16 (11.3%)
• Others 0 1 (0.7%)
Grade: 0.946a
• I 2 (12.5%) 14 (9.9%)
• II 9 (56.2%) 83 (58.9%)
• III 5 (31.2%) 44 (31.2%)
Molecular subtype: 0.801a
• Luminal A 5 (31.2%) 35 (24.8%)
• Luminal B 7 (43.8%) 80 (56.7%)
• Triple negative 3 (18.8%) 20 (14.2%)
• HER2+ 1 (6.2%) 6 (4.3%)
Ki-67: 0.507a
• <14% 1 (6.2%) 14 (9.9%)
• ≥14% 8 (50%) 85 (60.3%)
• Not assessed 7 (43.8%) 42 (29.8%)
N-stage: 0.823a
• N0 5 (31.2%) 48 (34%)
• N1-3 11 (68.8%) 93 (66%)
M-stage: 0.862a
• M0 13 (81.2%) 117 (83%)
• M1 3 (18.8%) 24 (17%)
  1. aChi-square test, bMann-Whitney U test