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Table 2 Distribution of COVID-19 and H1N1 patients according to predominant HRCT finding with statistical analysis of significance

From: COVID-19 versus H1N1: challenges in radiological diagnosis—comparative study on 130 patients using chest HRCT

HRCT findings

COVID-19

H1N1

X2

P value

N (65)

%

N (65)

%

Site of the pathology:

Bilateral

55

84.6%

60

92.3%

1.88

0.17

Unilateral

10

15.4%

5

7.7%

1.88

0.17

  Mixed

50

76.9%

55

84.6%

1.24

0.27

  Lower lobar only

10

15.4%

7

10.8%

0.61

0.44

  Upper lobar only

5

7.7%

3

4.6%

0.53

0.47

   Diffuse/mixed

30

46.2%

35

53.8%

0.77

0.38

   Sub-pleural

34

52.3%

30

46.2%

0.49

0.48

   Proximal

1

1.5%

Not detected

1

0.32

HRCT findings related to parenchymal or alveolar pathology (GGOs):

Mild stage:

50

76.9%

44

67.7%

  

  Pure ground glass nodules or patchy opacities (GGOs).

18 (36%)

27.7%

10 (22.7%)

15.4%

1.97

0.16

  GGOs showing peripheral organization “Atoll sign”

13 (26%)

20%

7 (15.9%)

10.8%

1.42

0.23

  GGOs mixed with consolidative changes.

19 (38%)

29.2%

27 (61.3%)

41.5%

5.11

0.02

Severe or critical stage:

15

23.1%

15

23.1%

  

  GGOs mixed with consolidative changes.

1 (7%)

1.5%

Not detected

1

0.31

  GGOs mixed with fibrotic changes.

1 (7%)

1.5%

Not detected

1

0.31

  “Crazy paving pattern” (part of DAD or ARDS)

13 (86%)

20%

15 (100%)

23.1%

2.14

0.14

HRCT findings related to bronchial/bronchiolar airway pathology: (N.B: either isolated or mixed with alveolar pattern, all were mild)

 Tree in bud nodules

1

1.5 %

9

13.8%

6.93

0.008*

 Air trapping

Not detected

7

10.8%

7.4

0.007*

 Bronchial wall thickening

Not detected

5

7.7%

5.2

0.02*

 Traction bronchiectasis

Not detected

5

7.7%

5.2

0.02*

 Mucous plugging

Not detected

4

6.2 %

4.13

0.04*

 Mixed air trapping and GGO “Head cheese pattern”

Not detected

3

4.6%

3.07

0.08

Relevant associated HRCT findings:

 Pleural effusion

3

4.6%

7

10.8%

1.73

0.19

 Pericardial effusion

2

3.1%

6

9.2%

2.13

0.14

 Cavitation

1

1.5%

1

1.5%

0

1

 Significant L.N enlargement

7

10.8%

5

7.7%

0.37

0.54

  1. *P value < 0.05 is considered clinically significant