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Table 1 Comparison between the strengths and the drawbacks of the contrast-based techniques used for breast imaging

From: Contrast-enhanced mammography in comparison with dynamic contrast-enhanced MRI: which modality is appropriate for whom?

  Contrast mammography MRI protocol
Contrast IV water soluble
1.5–2 mL/kg
IV Gadolinium Gadopentate
0.1 mmol/k
Patient position Erect Prone
Sequences/positions A pair of low- and high-energy images in the standard CC and MLO views Pre-contrast T1 and T2WI
Post-contrast dynamic and subtraction sequences
Dynamic sequences No Yes
Subtraction Post-contrast low from high-energy images Pre- from post-contrast images
Additional mammogram needed No Yes
Exam time 7–10 min 10–20 min
Interpretation time Faster than MRI 10 min
Irradiation exposure Yes No
Contraindications Pregnancy
Renal impairment
Allergy to contrast medium
Pregnancy
Renal impairment
Claustrophobia
Unable to lie prone
Incompatible devices
Body weight
Allergy with known anaphylactic shock (less common than CEM)
Risk from contrast Allergy No reported significant risk
Incorporation into daily practice Yes No
Cost Low cost Higher cost (as the used contrast media is expensive, the printed number of films is higher, the duration of the machine exhaustion is longer and an additional cost of mammogram may be needed)