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Table 3 Diagnostic accuracy of prenatal ultrasound (US) and prenatal MRI of fetal congenital anomalies

From: Added value of fetal MRI as a complementary method to antenatal ultrasound in the assessment of non-CNS fetal congenital anomalies

 

Pathology

Sensitivity 95% CI

Specificity

95% CI

PPV

95% CI

NPV

95% CI

Accuracy

95% CI

P value

Positive

(n = 30)

Negative

(n = 0)

No

%

No

%

Total sample (n = 30)

The prenatal US

    

76% (0.56, 0.82)

0% (0.0, 1.0)

100% (0.91, 1.0)

0% (0.0, 0.21)

76% (0.56, 0.82)

 < 0.0001*

Positive

23

76.6

0

0

Negative

7

23.2

0

0

Prenatal MRI

    

96.6% (0.82, 0.98)

0% (0.0, 1.0)

100% (0.93, 1.0)

0% (0.0, 0.60)

96.6% (0.82, 0.98)

0.04*

Positive

29

96.5

0

0

Negative

1

3.3

0

0

Combined MRI/US

    

100% (0.93, 1.0)

0% (0.0, 1.0)

100% (0.93, 1.0)

0% (0.0, 0.60)

100% (0.93, 1.0)

–

Positive

30

100

0

0

Negative

0

0

0

0

  1. Values in parentheses are 95% CI. Diagnostic accuracy of each technique compared using McNemar’s test with p < 0.05