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Table 2 Clinical parameters in patients with small, normal-sized and enlarged spleens, respectively, with clinically mild or severe Covid-19 infection

From: Splenomegaly versus pathological lung volume during COVID-19 infection with or without cytokine storm; a linear regression analysis using CT volumetry

Clinical parameter Normal-sized spleen, clinically mild disease Normal-sized spleen, clinically severe disease Small spleen, clinically severe disease Splenomegaly, clinically mild disease Splenomegaly, clinically severe disease
Splenic size n = 250 (49%) n = 9 (2%) n = 250 (49%)
Clinically mild disease, O2 Sat ≥ 93% n = 192 (76%)    n = 184 (74%)  
Clinically severe disease, O2 Sat < 93%   n = 58 (24%) n = 9 (100%)   n = 66 (26%)
Pathological lung volume 97% of patients → 0–20% (score 1) All patients → 23–71% (score 1–3) All patients → 34–55% (score 2 & 3) 97% of patients → 0–20% (score 1) All patients → 27–73% (Score 2 & 3)
Splenic volume at follow-up CT 100% unchanged 100% unchanged 100% unchanged 87% unchanged, 13% regression 75% unchanged, 25% progression