Splenomegaly versus pathological lung volume during COVID-19 infection with or without cytokine storm; a linear regression analysis using CT volumetry

Egyptian Journal of Radiology and Nuclear Medicine

Table 2 Clinical parameters in patients with small, normal-sized and enlarged spleens, respectively, with clinically mild or severe Covid-19 infection

Clinical parameter	Normal-sized spleen, clinically mild disease	Normal-sized spleen, clinically severe disease	Small spleen, clinically severe disease	Splenomegaly, clinically mild disease	Splenomegaly, clinically severe disease
Splenic size	n = 250 (49%)		n = 9 (2%)	n = 250 (49%)
Clinically mild disease, O2 Sat ≥ 93%	n = 192 (76%)			n = 184 (74%)
Clinically severe disease, O2 Sat < 93%		n = 58 (24%)	n = 9 (100%)		n = 66 (26%)
Pathological lung volume	97% of patients → 0–20% (score 1)	All patients → 23–71% (score 1–3)	All patients → 34–55% (score 2 & 3)	97% of patients → 0–20% (score 1)	All patients → 27–73% (Score 2 & 3)
Splenic volume at follow-up CT	100% unchanged	100% unchanged	100% unchanged	87% unchanged, 13% regression	75% unchanged, 25% progression