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Table 1 Demographics and clinical characteristics of IIM patients

From: Treatment-naïve idiopathic inflammatory myopathy: disease evaluation by fluorodeoxyglucose versus pyrophosphate

Pt. no.

Age (y)

Sex

Diagnosis, clinical

Diagnosis, ACR/EULAR criteria, IIM probability (%)

Cancer (Y/N)

Muscle weakness (Y/N)

Muscle biopsy

Skin manifestations

Dysphagia (Y/N)

Autoantibodies (MSA/MAA)

Increased CK level (Y/N)

PYP uptake

FDG uptake

1

75.5

F

IMNM

Probable IIM (86%), subgroup PM (IMNM)

N

Y

Inflammatory infiltrates

None

Y

Anti-SRP

Y

+

+

2

74.7

M

CAM

Definite IIM (100%), subgroup DM

Y

Y

No inflammation or perifascicular atrophy

Heliotrope rash, Gottron’s papules

Y

None

Y

+

++

3

40.1

F

DM

Definite IIM (100%), subgroup DM

N

Y

No inflammation or perifascicular atrophya

Heliotrope rash, Gottron’s papules

Y

None

Y

+

+

4

70.0

F

DM

Definite IIM (100%), subgroup DM

N

Y

Inflammatory infiltrates

Heliotrope rash, Gottron’s papules

Y, feeding tube

None

Y

+

+++

5

70.4

M

IMNM

Possible IIM (53%)

N

Y

Necrosis

None

Y

None

Y

+

++

6

76.7

F

CAM

Definite IIM (100%), subgroup DM

Y

Y

Inflammatory infiltrates

Heliotrope rash, Gottron’s papules

N

None

N

++

+

7

79.6

F

PM

Probable IIM (86%), subgroup PM (IMNM)

N

Y

Inflammatory infiltrates

None

Y, feeding tube

Anti-Ro52

Y

++

+

8

21.3

F

IMNM

Probable IIM (62%), subgroup PM (IMNM)

N

Y

Inflammatory infiltrates and necrosis

None

N

Anti-HMGCR

Y

NA

+

  1. MSA/MAA: myositis-specific autoantibody/myositis-associated autoantibody (anti-Mi-2, SRP, PL-7, PL-12, OJ, EJ, Jo1, PM-Scl75/100, Ro52, KU, not including anti-NXP2, TIF1γ, SAE1, MDA5, cN1A, HMGCR, except patient number 8)
  2. y years, Y yes, N no
  3. aElectron microscopy with undulating tubules