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Table 3 Validity of FA genue, splenium and CS tracts in discriminating trauma cases from controls

From: Altered diffusion tensor imaging (DTI) parameters in brain parenchyma after traumatic brain injury

FA

 

AUC (95% CI)

P value

Cutoff point

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Genue

Right

0.944 (0.864–1.0)

0.001*

0.7505

91.7

83.3

95.7

71.4

96.7

Left

0.896 (0.782–1.0)

0.003*

0.682

87.5

83.3

95.5

62.5

86.7

Splenium

Right

0.972 (0.919–1.0)

< 0.001*

0.8152

95.8

83.3

95.8

83.3

93.3

Left

0.938 (0.851–1.0)

0.001*

0.820

91.7

83.3

95.7

71.4

90.0

CS

Right

0.854 (0.721–0.987)

0.008*

0.600

79.2

83.3

95.0

50.0

80.0

Left

0.875 (0.747–1.0)

0.005*

0.646

83.3

66.7

90.9

50.0

80.0

  1. *Significance of FA alone, MD alone and combined FA and MD
  2. AUC—area under curve, PPV—positive predictive value, NPV—negative predictive value