Altered diffusion tensor imaging (DTI) parameters in brain parenchyma after traumatic brain injury

Egyptian Journal of Radiology and Nuclear Medicine

Table 5 Validity of combined FA & MD in differentiating cases with trauma

Combined FA & MD	AUC (95% CI)	P value	cutoff point by probability of multivariate	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)
SLF	0.799 (0.585–1.0)	0.02*	.7541514	87.5	66.7	91.3	57.1	83.3
AF	0.937 (0.849–1.0)	0.001*	.8464303	83.3	83.3	95.2	55.6	83.3
Genu	1.0 (1.0–1.0)	< 0.001*	.500000	100.0	100.0	100.0	100.0	100.0
Splenium	1.0 (1.0–1.0)	< 0.001*	.500000	100.0	100.0	100.0	100.0	100.0
ILF	0.785 (0.598–0.972)	0.034*	.7606485	79.2	66.7	90.5	44.4	76.7
CS	0.951 (0.878–1.0)	0.001*	0.7615	87.5	83.3	95.5	62.5	86.7

*Significance of FA alone, MD alone and combined FA and MD
AUC—area under curve, PPV—positive predictive value, NPV—negative predictive value
Cutoff point for saved probability by regression