Fig. 3

A 26-year-old pregnant female with a routine 2nd trimester 4D US showing large ventral abdominal wall defect. Ultrasound findings (A), B axial sections of the fetal abdomen show a large central abdominal wall defect with herniation of the right hepatic lobe and bowel loops through. C, D sagittal 4D images revealing clenched hands and rocker bottom feet deformity. MRI findings: E, H sagittal T2WIs showing herniated liver and small bowel loops with an overlying thin membrane and associated rocker bottom feet. F, G axial T2WIs showing the size of the hernia defect, content as well as clenched hand. I sagittal T1WIs showing meconium signals within herniated bowel distal ileal loops. Diagnosis: The combination of skeletal anomalies with large Omphalocele suggested underlying chromosomal abnormality and trisomy 18 was diagnosed by postnatal chromosomal analysis. Termination by C.S. at 37 weeks