Preoperative prediction of Ki-67 status in invasive breast carcinoma using dynamic contrast-enhanced MRI, diffusion-weighted imaging and diffusion tensor imaging

Egyptian Journal of Radiology and Nuclear Medicine

Table 3 Cut off values, sensitivity, specificity and accuracy of ADC, maximum enhancement, washout ratio & time to peak in differentiating between low and high Ki67 status

Test Result Variable(s)	Area	p	Asymptotic 95% Confidence Interval		Cut off point	Sensitivity%	Specificity%	PPV%	NPV%	Accuracy%
Test Result Variable(s)	Area	p	Lower Bound	Upper Bound	Cut off point	Sensitivity%	Specificity%	PPV%	NPV%	Accuracy%
ADC	0.777	0.002*	0.557	0.996	0.657	96.4	75.0	96.4	75.0	93.8
Max enhancement	0.830	0.001*	0.662	0.999	1715	96.4	75.0	96.4	75.0	93.8
Washout ratio	0.679	0.045*	0.577	0.780	0.730	60.7	75.0	94.4	21.4	62.5
Time to peak	0.679	0.046*	0.544	0.813	304	71.4	75	95.2	27.3	71.9