Suspicious lung lesions for malignancy: the lesion-to-spinal cord signal intensity ratio in T2WI and DWI–MRI versus PET/CT; a prospective pathologic correlated study with accuracy and ROC analyses

Egyptian Journal of Radiology and Nuclear Medicine

Table 1 Inter-rater reliability and intra-class correlation coefficient (ICC)

	No.	1st group reading	2nd group reading	P-value	ICC	95% CI	Level of agreement
T2WI based L-to-SC SI ratio
Malignant	28	1.35 ± 0.29	1.32 ± 0.31	< 0.001^*	0.899	0.794–0.952	Good
Benign	15	0.88 ± 0.40	0.89 ± 0.33	< 0.001^*	0.941	0.833–0.980	Excellent
Overall	43	1.19 ± 0.40	1.17 ± 0.37	< 0.001^*	0.942	0.896–0.968	Excellent
b500-DWI based L-to-SC SI ratio
Malignant	28	1.05 ± 0.41	1.08 ± 0.37	< 0.001^*	0.922	0.840–0.963	Excellent
Benign	15	0.48 ± 0.30	0.50 ± 0.24	< 0.001^*	0.911	0.760–0.969	Excellent
Overall	43	0.85 ± 0.46	0.88 ± 0.43	< 0.001^*	0.950	0.909–0.972	Excellent
Mean ADC value in 10⁻³mm²/s
Malignant	28	1.10 ± 0.27	1.15 ± 0.32	< 0.001^*	0.845	0.711–0.915	Good
Benign	15	1.19 ± 0.26	1.23 ± 0.32	< 0.001^*	0.890	0.729–0.958	Good
Overall	43	1.13 ± 0.29	1.18 ± 0.32	< 0.001^*	0.861	0.760–0.927	Good
Minimum ADC value in 10⁻³mm²/s
Malignant	28	0.80 ± 0.29	0.85 ± 0.33	< 0.001^*	0.851	0.705–0.928	Good
Benign	15	0.89 ± 0.28	0.93 ± 0.31	< 0.001^*	0.897	0.727–0.964	Good
Overall	43	0.83 ± 0.29	0.88 ± 0.32	< 0.001^*	0.865	0.762–0.925	Good