Quantitative analysis of white matter brain changes in tinnitus patients with normal hearing: a case-controlled study with diffusion tensor imaging

Eltabbakh, Amira; Nada, Nashwa

doi:10.1186/s43055-023-01024-x

Egyptian Journal of Radiology and Nuclear Medicine

Table 3 Comparison between study (Tinnitus) and control (NH) group as regards mean diffusity (MD) measured at different brain sites

From: Quantitative analysis of white matter brain changes in tinnitus patients with normal hearing: a case-controlled study with diffusion tensor imaging

MD	Tinnitus group Mean ± SD	Control group Mean ± SD	Tinnitus group median (IQ range)	Control group median (IQ range)	p value	Parametric (t) test /nonparametric Mann–Whitney (U)
Rt LL	0.8064 ± 0.2593	0.9557 ± 0.7473	0.8100 (0.5850–0.8350)	0.7950 (0.6450–0.9450)	0.9367	U = 96
Lt LL	0.7657 ± 0.08455	0.7643 ± 0.07079	0.7300 (0.6975–0.8450)	0.7750 (0.7350–0.8300)	0.6423	U = 87.5
Right IC	1.040 ± 0.9507	0.8686 ± 0.2043	0.7750 (0.5750–0.9200)	0.8200 (0.7400–0.9250)	0.3944	U = 79
Left IC	0.8321 ± 0.1683	0.8336 ± 0.1280	0.7600 (0.6950–1.008)	0.8050 (0.7375–0.8750)	0.6587	U = 88
Right MGB	1.023 ± 0.2721	0.9857 ± 0.3440	0.9950 (0.8300–1.238)	0.9450 (0.8000–1.043)	0.7539	t = 0.3168, df = 26
Left MGB	0.9171 ± 0.05663	0.9014 ± 0.1490	0.9150 (0.8575–0.9700)	0.8750 (0.7950–0.9525)	0.2402	U = 72
Right AC	0.8393 ± 0.1228	0.7314 ± 0.06792	0.8850 (0.7225–0.9600)	0.6950 (0.6900–0.8200)	0.0181	U = 47.5
Left AC	0.7836 ± 0.1035	0.7729 ± 0.09911	0.7700 (0.6850–0.9025)	0.8000 (0.6675–0.8600)	0.7819	t = 0.2797, df = 26
Right AMG	0.8550 ± 0.1140	0.7707 ± 0.08052	0.8350 (0.7700–0.9700)	0.7950 (0.6950–0.8400)	0.0325	t = 2.260, df = 26
Left AMG	0.8514 ± 0.08356	0.9493 ± 0.2464	0.8400 (0.7875–0.9000)	0.8600 (0.7600–1.070)	0.1785	t = 1.407, df = 15.95
Right hippocampus	0.8771 ± 0.2060	0.8093 ± 0.3012	0.8650 (0.6200–1.0480	0.8350 (0.6725–1.043)	0.4928	t = 0.6958, df = 26
Left hippocampus	0.8171 ± 0.1176	0.8407 ± 0.1015	0.8600 (0.7475–0.9325)	0.8450 (0.7800–0.8975)	0.5751	t = 0.5677, df = 26
Right para hippocampus	0.8521 ± 0.09341	0.8871 ± 0.1941	0.8400 (0.7725–0.9500)	0.7950 (0.7375–1.058)	0.8829	U = 94.50
Left para hippocampus	0.8386 ± 0.1762	0.9021 ± 0.1549	0.7950 (0.7000–0.9400)	0.9000 (0.7575–1.050)	0.3201	t = 1.014, df = 26
Right frontal AF	0.8571 ± 0.1466	0.7393 ± 0.09499	0.9250 (0.6900–0.9300)	0.7450 (0.6600–0.8000)	0.0113	U = 44
Left frontal AF	0.7386 ± 0.08565	0.7336 ± 0.1137	0.7400 (0.7050–0.8050)	0.7000 (0.6575–0.7925)	0.8965	t = 0.1314, df = 26
Right Parietal AF	0.7700 ± 0.1766	0.7779 ± 0.1044	0.7400 (0.6000–0.9400)	0.7600 (0.6950–0.8225)	0.8872	t = 0.1433, df = 26
Left parietal AF	0.7657 ± 0.08821	0.7336 ± 0.08509	0.7800 (0.7500–0.8300)	0.7050 (0.6500–0.8325)	0.3003	U = 75
Splenium	0.8957 ± 0.2631	0.8164 ± 0.1294	0.8200 (0.7400–0.9700)	0.8300 (0.7350–0.8900)	0.7946	U = 92
Genu	0.8014 ± 0.1019	0.9607 ± 0.3256	0.7900 (0.7000–0.9100)	0.8650 (0.7300–1.103)	0.1004	t = 1.747, df = 15.52

Areas that showed significant levels of changes between two groups are expressed in bold
AC: auditory cortex, AF: arcuate fasciculus, AMG: amygdala,, IC: inferior colliculus, LL: lateral lemniscus, Lt: left, MD: mean diffusity, MGB: medial geniculate body, Rt: right

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