Table 1 Univariate and multivariate analysis of clinical and pathological variables for relapse
Clinicopathological factors | Total | Relapse (%) | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|---|---|
No | Yes | P value | P value | Odds ratio | 95% CI | ||||
Total | 72 | 57 (79) | 15 (21) | ||||||
Clinical factors | |||||||||
Age (mean: 69, range 23–94) | |||||||||
< 70 | 30 | 25 (83) | 5 (17) | 0.56 | |||||
≥ 70 | 42 | 32 (76) | 10 (24) | ||||||
Sex | |||||||||
Male | 32 | 25 (78) | 7 (22) | 0.85 | |||||
Female | 40 | 32 (80) | 8 (20) | ||||||
Primary site | |||||||||
Tongue | 41 | 31 (76) | 10 (24) | 0.56 | |||||
Other | 31 | 26 (84) | 5 (16) | ||||||
S-1 chemotherapy | |||||||||
− | 30 | 25 (83) | 5 (17) | 0.43 | |||||
+ | 42 | No-responder | 32 | 23 (55) | 9 (45) | 0.42 | |||
Responder | 10 | 9 (90) | 1 (10) | ||||||
cT | |||||||||
T1/ T2 | 48 | 41 (85) | 7 (15) | 0.07 | |||||
T3/ T4 | 24 | 16 (67) | 8 (33) | ||||||
FDG PET suv max | |||||||||
Low (< 9.5) | 44 | 39 (89) | 5 (11) | 0.019 | 0.10 | ||||
High (≥ 9.5) | 28 | 18 (64) | 10 (36) | ||||||
Pathological factor | |||||||||
PDL-1 | |||||||||
Low (< 25%) | 40 | 33 (83) | 7 (17) | 0.51 | |||||
High (≥ 25%) | 32 | 24 (75) | 8 (25) | ||||||
CD8 | |||||||||
Low | 39 | 31 (79) | 8 (21) | 0.93 | |||||
High | 33 | 26 (79) | 7 (21) | ||||||
CD15 | |||||||||
Low | 27 | 25 (93) | 2 (7) | 0.017 | 0.028 | 0.171 | 0.035–0.827 | ||
High | 45 | 32 (71) | 13 (29) | ||||||
S100A8 | |||||||||
Low | 24 | 22 (92) | 2 (8) | 0.025 | 0.36 | ||||
High | 48 | 35 (73) | 13 (27) | ||||||
CD33 | |||||||||
Low | 33 | 26 (79) | 7 (21) | 0.59 | |||||
High | 39 | 31 (79) | 8 (21) | ||||||