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Table 6 Discriminating thresholds and diagnostic performance of D-value for distinguishing moderate from mild COPD using forced expiratory volume in the first second (FEV1) spirometric parameter as a reference (gold) standard

From: Assessment of artificial intelligence-aided chest computed tomography in diagnosis of chronic obstructive airway disease: an observational study

Coordinates of ROC curve

Threshold for achieving optimal sensitivity and specificity

Threshold for achieving near-90% sensitivity

Threshold for achieving near-90% specificity

AUC

0.573

Standard error

0.085

95%CI

0.406–0.740

p value

0.340

Cut-off

 ≥ − 5.0

 ≥ − 5.3

 ≥ − 3.8

Sensitivity

 TP/(TP + FN)

77.0%

89.7%

18.0%

Specificity

 TN/(TN + FP)

48.0%

39.1%

87.0%

  1. ROC curve receiver operating characteristics curve, AUC area under ROC curve, CI confidence interval, TP true positive, FN false negative, TN true negative, FP false positive