Fig. 3

A 32-year-old female patient with history of MS, follow-up MRI is requested as active disease is clinically suspected. Each row is composed of images at the same level. A and B: axial pre-contrast FLAIR shows multiple high signal intensity plaques seen at periventricular white matter (A) as well as centrum semiovale and subcortical white matter of both cerebral hemispheres (B). C and D: axial post-contrast FLAIR where plaques appear more bright (yellow arrows) and the left subcortical lesion in D becomes more clearly demonstrated and even larger in size (red arrow). E and F: Subtraction FLAIR images confirmed the enhancement of the lesions (arrows). G and H: axial post-contrast T1WI: no definite enhancing lesions could be detected