Fig. 4

A 31-year-old female patient presented by numbness, weakness and fatigue. A Coronal pre-contrast FLAIR shows: few foci of high signal intensity at subcortical and periventricular white matter. B Coronal post-contrast FLAIR shows nodular enhancement at two lesions (arrows) which appear ultrabright than in A, with the lesion at right temporal lobe not visualized in post-contrast T1WI (E). C and D Coronal pre- and post-contrast FLAIR at the same level as A and B with measurements of the signal intensity shown, denoting the difference between pre- and post-contrast images and confirming presence of enhancement. E Coronal post-contrast T1WI shows subtle non-clearly demonstrated incomplete ring enhancement of the left periventricular lesion in comparison with B. Diagnosis: MS with radiological signs of activity