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Table 1 The Manchester diagnostic criteria for neurofibromatosis type 2 [2]

From: Giant sacral schwannoma in a neurofibromatosis type 2 patient

Key finding

Additional findings needed for diagnosis

Bilateral vestibular schwannomas

None

Family history

Unilateral vestibular schwannoma or two NF2-associated lesions like schwannoma, glioma, meningioma, or neurofibroma

Unilateral vestibular schwannoma

Two NF2-associated lesions

Multiple meningiomas

Unilateral vestibular schwannoma or two other NF2-associated lesions