Table 3 MRI morphological features stratified by molecular subtypes
From: Relation between morphological features of initial breast MRI and breast cancer molecular subtypes
Morphological features | Molecular subtypes | P value | |||
|---|---|---|---|---|---|
Luminal A (n = 15) | Luminal B (n = 7) | HR-HER2 positive (n = 5) | TNBC (n = 3) | ||
N (%) | N (%) | N (%) | N (%) | ||
Mass shape | |||||
Round | 6 (40%) | 4 (57.1%) | 1 (20%) | 3 (100%) | 0.098 |
Oval | 1 (6.7%) | 1 (14.3%) | 1 (20%) | 0 (0%) | 0.345 |
Irregular | 7 (46.7%) | 2 (28.6%) | 3 (60%) | 0 (0%) | 0.112 |
Non-mass enhancement | 1 (6.7%) | 0 (0%) | 0 (0%) | 0 (0%) | 1.00 |
Mass border | |||||
Speculated | 12 (80%) | 3 (42.9%) | 4 (80%) | 0 (0%) | 0.023* |
Irregular | 2 (13.3%) | 3 (42.9%) | 1 (20%) | 2 (66.7%) | 0.188 |
Angulated | 1 (6.7%) | 0 (0%) | 0 (0%) | 1 (33.3%) | 0.161 |
Well-defined | 0 (0%) | 1 (14.3%) | 0 (0%) | 0 (0%) | 1.00 |
Multicentricity | |||||
Unicentric | 4 (26.7%) | 2 (28.6%) | 2 (66.7%) | 3 (60%) | 0.386 |
Multicentric | 11 (73.3%) | 5 (71.4%) | 1 (33.3%) | 2 (40%) | |
Tumor size | |||||
T1 | 0 (0%) | 1 (14.3%) | 1 (20%) | 0 (0%) | 0.602 |
T2 | 9 (60%) | 3 (42.9%) | 3 (60%) | 1 (33.3%) | |
T3 | 3 (20%) | 0 (0%) | 0 (0%) | 1 (33.3%) | |
T4 | 3 (20%) | 3 (42.9%) | 1 (20%) | 1 (33.3%) | |
Lymph nodes | |||||
Positive | 4 (26.7%) | 0 (0%) | 0 (0%) | 1 (33.3%) | 0.283 |
Negative | 11 (73.3%) | 7 (100%) | 5 (100%) | 2 (66.7%) | |