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Table 3 ROC shows Cut off value of rAPT, ADC,rCBVand Cho/cr for predicting high-grade tumor

From: The added value of relative amide proton transfer (rAPT) to advanced multiparametric MR imaging for brain glioma characterization

Ā 

AUC

95% CI

P value

Cut off

TP

TN

FP

FN

Sen

Spe

PPV

NPV

Acc

rAPT

0.941

0.895ā€“0.986

<ā€‰0.001*

1.315#

61

32

6

3

95.3

84.2

91

91.4

91.2

ADC mean

0.907

0.853ā€“0.961

<ā€‰0.001*

1.125+

46

33

5

18

71.9

86.8

90.2

64.7

77.5

rCBV Tumor

0.906

0.580ā€“0.961

<ā€‰0.001*

2.365#

60

27

11

4

93.8

71.1

84.5

87.1

85.3

Cho/Cr

0.797

0.712ā€“0.882

<ā€‰0.001*

1.69#

48

23

15

16

75

60.5

76.2

59

69.6

  1. Total number of brain tumors with edema is 53 brain SOL
  2. * indicates significant
  3. +indicates equal or less than cut off value
  4. #indicates equal or greater than cut off value