The application of dual-phase enhanced CT scan in distinguishing adrenal ganglioneuromas from adrenal lipid-poor adenomas

Egyptian Journal of Radiology and Nuclear Medicine

Table 3 Diagnostic performance of CT values, age, and mean diameter for ganglioneuromas vs lipid-poor adenomas

	AUC	95% CI	Cut-off value (%)	Sensitivity%	Specificity%
CT_U	0.713	0.650 ~ 0.775	≤ 22.5 HU	46.8	100
CT_A	0.878	0.836 ~ 0.920	≥ 51.5 HU	67.6	100
CT_V	0.914	0.876 ~ 0.952	≥ 53.5 HU	88.0	88.1
Age	0.798	0.605 ~ 0.821	≥ 50.5 years	63.4	85.7
Mean D	0.758	0.679 ~ 0.837	≤ 28.3 mm	45.2	93.1

Forty-two adrenal ganglioneuromas and 216 lipid-poor adenomas were evaluated. The criterion value was determined by the maximum value of Youden’s index (sensitivity + specificity − 1)
AUC Area under the receiver operating characteristic curve, CT_U CT value of unenhanced, CT_A CT value of arterial phase, CT_V CT value of venous phase, Mean D Mean dimension