Multi-phasic magnetic resonance imaging of hemodynamic interchanges in hepatocarcinogenesis

Egyptian Journal of Radiology and Nuclear Medicine

Table 2 Hepatocarcinogenesis hemodynamics (diagnostic performances)

Data	Significance	ROC	95% CI	Cut off	Sensitivity	Specificity
Liver C versus liver N
WOR	****	0.81	0.75–0.87	< 1.25 L/s	0.67	0.82
T Peak	****	0.80	0.73–0.86	> 63 s	0.67	0.76
r AUC	**	0.63	0.55–0.72	> 25%	0.60	0.67
Nodule D versus liver C
MRE	****	0.74	0.64–0.84	< 56%	0.59	0.82
T Zero	*	0.62	0.49–0.76	< 14 s	0.52	0.80
HCC N versus nodule D
MRE	****	0.88	0.82–0.94	> 83%	0.74	0.82
WIR	****	0.84	0.76–0.92	> 18 L/s	0.78	0.75
WOR	****	0.78	0.69–0.77	> 2.2 L/s	0.68	0.70
T Peak	***	0.74	0.64–0.84	< 55.5 s	0.55	0.85
AUC	****	0.73	0.63–0.83	> 79.5 L/100 ml	0.77	0.59
T Zero	**	0.70	0.58–0.82	< 7 s	0.83	0.56
HCC R versus HCC N
r AUC	**	0.66	0.56–0.75	> 47%	0.50	0.80
T Peak	**	0.66	0.57–0.76	> 65 s	0.53	0.78
MRE	*	0.63	0.54–0.72	> 115%	0.50	0.62

More asterisk indicate the more significance
Liver N Non-cirrhotic liver, Liver C Cirrhotic liver, Nodule D Indeterminate dysplastic nodule, HCC N De novo HCC, HCC R Recurrent HCC, Ablated R Recurrence after ablation, MRE Maximum relative enhancement, WIR Wash-in ratio, WOR Washout ratio, T Peak Time to peak, T Zero Time to arrival, AUC Area under the curve