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Table 3 CT characterization of benign and malignant GB wall thickening

From: Clinical approach to patients with thick wall gallbladder

CT findings

Benign

Malignant

Thickening

Diffuse, symmetrical

Focal, asymmetrical

Enhancement

(a) Single layer: Homogenous

(b) Two layered patterns: Inner layer iso-attenuating to liver

(a) Thick one layer with heterogeneous enhancement

(b) Two layers: Strongly enhancing thick inner layer (≥ 2.6 mm) with weakly enhancing or non-enhancing thin outer layer

Bile duct obstruction

Uncommon

More common

Lymphadenopathy

Usually absent

Mostly present

Adjacent organ infiltration

Not seen commonly

Present in advanced disease