Structural integrity of grey and white matter in schizophrenic patients by diffusion tensor imaging

Egyptian Journal of Radiology and Nuclear Medicine

Table 3 Comparison between schizophrenic patients and control group regarding fractional anisotropy, apparent diffusion coefficient and mean diffusivity values of right thalami and right basal ganglia

	Groups		Mann–Whitney test
	Control (n = 25)	Patients (n = 25)	Z	p value
Right thalamus Fractional anisotropy
Median [IQR]	0.25 [0.20–0.32]	0.25 [0.22–0.28]	0.897	0.370
Min–Max	0.20–0.39	0.17–0.37
Apparent diffusion coefficient × 10^–3 mm²/s
Median [IQR]	0.89 [0.79–0.93]	0.85 [0.77–0.90]	1.371	0.170
Min–Max	0.75–1.01	0.70–0.97
Mean diffusivity × 10^–9 mm²/s
Median [IQR]	2.30 [2.00–2.70]	3.10 [2.80–3.44]	5.167	< 0.001*
Min–Max	1.80–3.00	2.50–3.80
Right basal ganglion Fractional anisotropy
Median [IQR]	0.25 [0.20–0.30]	0.20 [0.19–0.22]	1.961	0.050*
Min–Max	0.12–0.35	0.08–0.27
Apparent diffusion coefficient × 10^–3 mm²/s
Median [IQR]	0.80 [0.76–0.88]	0.78 [0.76–0.84]	0.934	0.350
Min–Max	0.75–1.20	0.71–0.99
Mean diffusivity × 10^–9 mm²/s
Median [IQR]	1.80 [1.50–2.20]	3.00 [2.84–3.49]	5.981	< 0.001*
Min–Max	1.20–2.70	2.50–4.20

IQR interquartile range (25th–75th percentiles), Max maximum, Min minimum, n number
*Significant at p ≤ 0.05