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Table 4 Diagnostic ability of RA, FA, and MD in the prediction of mimics in comparison to control

From: Diffusion tensor imaging and voxel-based morphometry in differentiating multiple sclerosis and its mimics

Indices

Diagnostic criteria

RA

FA

MD

AUC

0.786

0.775

0.960

Cut off

 ≤ 0.267

 ≤ 0.315

 > 0.764*

Accuracy

78.5%

75.0%

94.5%

Sensitivity, %

85.2%

85.2%

96.3%

Specificity, %

71.4%

64.3%

92.9%

PPV, %

85.2%

82.1%

96.3%

NPP, %

71.4%

69.2%

92.9%

P value

 < 0.001

 < 0.001

 < 0.001

  1. Bold values indicate high statistical significant
  2. PPV positive predictive value, NPV negative predictive value, AUC area under the curve, RA relative anisotropy, FA fractional anisotropy, MD mean diffusivity
  3. *MD is presented in units of 10−3 mm2/s